Bir \u00e7ox elmi nailiyy\u0259tl\u0259r\u0259 baxmayaraq, x\u0259r\u00e7\u0259ng, h\u0259l\u0259 d\u0259 m\u00fcalic\u0259si \u00e7ox \u00e7\u0259tin olan bir x\u0259st\u0259likl\u0259rd\u0259n biridir. Ancaq indi x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rini intihara v\u0259 bir-biri il\u0259 m\u00fcbariz\u0259y\u0259 s\u00f6vq ed\u0259n bir \u00fcsul haz\u0131rlan\u0131b.<\/p>\n
Elm adamlar\u0131, x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rini\u00a0Troya atlar\u0131na\u00a0\u00e7evir\u0259n modulyar genetik sxem yarad\u0131blar. Bu modulyar sxem, d\u0259rmana davaml\u0131 x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rinin \u00f6z-\u00f6zl\u0259rini m\u0259hv etm\u0259kl\u0259rin\u0259 v\u0259 \u00f6ld\u00fcrm\u0259kl\u0259rin\u0259 imkan verir.\u00a0Burada \u0259sas yenilik iki genin v\u0259 ya iki yeni \u201ca\u00e7ar\u201d\u0131n t\u0259tbiqini n\u0259z\u0259rd\u0259 tutur. Birinci \u0259sas odur ki, genetik c\u0259h\u0259td\u0259n d\u0259yi\u015fdirilmi\u015f h\u00fcceyr\u0259l\u0259r, m\u00fc\u0259yy\u0259n bir d\u0259rmana m\u0259ruz qald\u0131qda x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259si populyasiyas\u0131n\u0131n qalan hiss\u0259si il\u0259 r\u0259qab\u0259t apar\u0131r, daha do\u011frusu, \u00fcst\u00fcnl\u00fck t\u0259\u015fkil edir. \u0130kinci a\u00e7ar is\u0259 daha sonra d\u0259yi\u015fdirilm\u0259mi\u015f qon\u015fular\u0131 il\u0259 birlikd\u0259 haz\u0131rda dominant olan d\u0259yi\u015fdirilmi\u015f h\u00fcceyr\u0259l\u0259ri \u00f6ld\u00fcr\u0259n bir toksin burax\u0131r.<\/p>\n
Nature\u00a0Biotechnology-d\u0259\u00a0n\u0259\u015fr olunan v\u0259 patent \u00fc\u00e7\u00fcn m\u00fcraci\u0259t edil\u0259n bu texnika, m\u00f6vcud x\u0259r\u00e7\u0259ng m\u00fcalic\u0259l\u0259ri il\u0259 \u0259sas problemi d\u0259f edir. M\u0259lum oldu\u011fu kimi, x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259ri,\u00a0m\u00fcalic\u0259d\u0259n sonra sa\u011f qalma\u011fa imkan ver\u0259n\u00a0m\u00fcqavim\u0259t mexanizml\u0259ri inki\u015faf etdir\u0259 bilirl\u0259r. Bu s\u0259b\u0259bd\u0259n x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259ri, bir m\u00fcdd\u0259t sonra m\u00fcalic\u0259 \u00fc\u00e7\u00fcn istifad\u0259 olunan d\u0259rmanlara qar\u015f\u0131 m\u00fcqavim\u0259t g\u00f6st\u0259r\u0259 bil\u0259rl\u0259r. Bunun qar\u015f\u0131s\u0131n\u0131 almaq \u00fc\u00e7\u00fcn h\u0259kiml\u0259r, tez-tez \u015fi\u015fl\u0259r\u0259 m\u00fcxt\u0259lif yollarla h\u00fccum ed\u0259n d\u0259rman birl\u0259\u015fm\u0259l\u0259rind\u0259n istifad\u0259 edirl\u0259r. Ancaq m\u00fcalic\u0259si \u00e7\u0259tin olan x\u0259r\u00e7\u0259ngl\u0259rd\u0259 bu se\u00e7iml\u0259r kifay\u0259t q\u0259d\u0259r m\u0259hduddur.<\/p>\n
Yeni texnika, tamamil\u0259 f\u0259rqli bir yana\u015fma t\u0259tbiq edir. O, yeni d\u0259rmanlar v\u0259 ya h\u0259d\u0259fl\u0259r tapmaq \u0259v\u0259zin\u0259,\u00a0\u015fi\u015fin s\u00fcr\u0259tl\u0259 t\u0259kam\u00fcl etm\u0259k qabiliyy\u0259tind\u0259n yararlan\u0131r\u00a0v\u0259 sad\u0259 bir \u015f\u0259kild\u0259 buna ona qar\u015f\u0131 istifad\u0259 edir. Bu ikiqat a\u00e7ar metodunun ilk add\u0131m\u0131nda elm adamlar\u0131 geni d\u0259yi\u015fdirilmi\u015f h\u00fcceyr\u0259l\u0259rin say\u0131n\u0131 \u00e7oxald\u0131r v\u0259 onlar\u0131 dominant edir, sonra ikinci a\u00e7ar\u0131 aktivl\u0259\u015fdirir. \u0130kinci a\u00e7ar, d\u0259yi\u015fdirilmi\u015f h\u00fcceyr\u0259l\u0259rin h\u0259m d\u0259yi\u015fdirilmi\u015f, h\u0259m d\u0259 qon\u015fu d\u0259yi\u015fdirilm\u0259mi\u015f h\u00fcceyr\u0259l\u0259ri \u00f6ld\u00fcr\u0259 bil\u0259n toksin istehsal etm\u0259sin\u0259 s\u0259b\u0259b olan intihar genini ehtiva edir. Bu, h\u0259qiq\u0259t\u0259n vacibdir. \u00c7\u00fcnki siz \u015fi\u015fin yenid\u0259n b\u00f6y\u00fcm\u0259sinin qar\u015f\u0131s\u0131n\u0131 almaq \u00fc\u00e7\u00fcn yox etm\u0259k ist\u0259diyiniz populyasiyan\u0131 mahiyy\u0259t etibar\u0131 il\u0259 aradan qald\u0131r\u0131rs\u0131n\u0131z.<\/p>\n
Bu texnikan\u0131n i\u015fl\u0259y\u0259c\u0259yini g\u00f6rm\u0259k \u00fc\u00e7\u00fcn komanda, si\u00e7anlar \u00fcz\u0259rind\u0259 a\u011fciy\u0259r x\u0259r\u00e7\u0259ngin\u0259 \u0259saslanan t\u0259cr\u00fcb\u0259l\u0259r apar\u0131b. T\u0259cr\u00fcb\u0259l\u0259r n\u0259tic\u0259sind\u0259 bir ovuc m\u00fch\u0259ndis h\u00fcceyr\u0259si x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rinin populyasiyas\u0131n\u0131 \u0259l\u0259 ke\u00e7ir\u0259 v\u0259 y\u00fcks\u0259k s\u0259viyy\u0259li genetik heterojenliyi aradan qald\u0131ra bilib. T\u0259dqiqat m\u0259qal\u0259sin\u0259 g\u00f6r\u0259, genetik c\u0259h\u0259td\u0259n d\u0259yi\u015fdirilmi\u015f h\u00fcceyr\u0259l\u0259r, 20 g\u00fcn \u0259rzind\u0259 orijinal h\u00fcceyr\u0259l\u0259r \u00fcz\u0259rind\u0259 dominant olaraq qal\u0131blar. 80-ci g\u00fcnd\u0259 is\u0259 \u015fi\u015fl\u0259r tamamil\u0259 geril\u0259yib. T\u0259dqiqat\u00e7\u0131lar, haz\u0131rda bu genetik sxemi, t\u0259hl\u00fck\u0259siz v\u0259 se\u00e7ici \u015f\u0259kild\u0259 b\u00f6y\u00fcy\u0259n \u015fi\u015fl\u0259r\u0259 v\u0259 n\u0259tic\u0259d\u0259 metastatik x\u0259st\u0259liy\u0259 t\u0259tbiq etm\u0259k \u00fc\u00e7\u00fcn nec\u0259 t\u0259rc\u00fcm\u0259 ed\u0259c\u0259kl\u0259ri \u00fcz\u0259rind\u0259 \u00e7al\u0131\u015f\u0131rlar.<\/p>\n
technote.az<\/p>\n","protected":false},"excerpt":{"rendered":"
Bir \u00e7ox elmi nailiyy\u0259tl\u0259r\u0259 baxmayaraq, x\u0259r\u00e7\u0259ng, h\u0259l\u0259 d\u0259 m\u00fcalic\u0259si \u00e7ox \u00e7\u0259tin olan bir x\u0259st\u0259likl\u0259rd\u0259n biridir. Ancaq indi x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rini intihara v\u0259 bir-biri il\u0259 m\u00fcbariz\u0259y\u0259 s\u00f6vq ed\u0259n bir \u00fcsul haz\u0131rlan\u0131b. Elm adamlar\u0131, x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rini\u00a0Troya atlar\u0131na\u00a0\u00e7evir\u0259n modulyar genetik sxem yarad\u0131blar. Bu modulyar sxem, d\u0259rmana davaml\u0131 x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rinin \u00f6z-\u00f6zl\u0259rini m\u0259hv etm\u0259kl\u0259rin\u0259 v\u0259 \u00f6ld\u00fcrm\u0259kl\u0259rin\u0259 imkan verir.\u00a0Burada \u0259sas yenilik iki […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[77],"tags":[],"_links":{"self":[{"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/posts\/213659"}],"collection":[{"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/comments?post=213659"}],"version-history":[{"count":2,"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/posts\/213659\/revisions"}],"predecessor-version":[{"id":213661,"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/posts\/213659\/revisions\/213661"}],"wp:attachment":[{"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/media?parent=213659"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/categories?post=213659"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.imm.az\/exp\/wp-json\/wp\/v2\/tags?post=213659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}