Donor qan\u0131na daim artan t\u0259l\u0259bat \u015f\u0259raitind\u0259, x\u00fcsusil\u0259 d\u0259 a\u015fa\u011f\u0131 v\u0259 orta g\u0259lirli \u00f6lk\u0259l\u0259rd\u0259, s\u00fcni qan \u0259v\u0259zedicil\u0259rinin haz\u0131rlanmas\u0131 m\u00fcasir tibbin \u0259n aktual v\u0259zif\u0259l\u0259rind\u0259n biridir. Nara Tibb Universitetind\u0259n (Yaponiya) Hiromi Sakai r\u0259hb\u0259rliyind\u0259ki t\u0259dqiqat qrupu bu sah\u0259d\u0259 m\u00fch\u00fcm ir\u0259lil\u0259yi\u015f \u0259ld\u0259 edib. Onlar\u0131n haz\u0131rlad\u0131qlar\u0131 s\u00fcni qan – ist\u0259nil\u0259n qan qrupu olan pasientl\u0259r \u00fc\u00e7\u00fcn uy\u011fun olan universal preparat – transfuziologiya\u00a0sah\u0259sind\u0259 \u0259sl inqilab v\u0259d edir. S\u00fcni qan\u00a0hemoqlobind\u0259n haz\u0131rlan\u0131r. Bu, donor qan\u0131n\u0131n istifad\u0259 m\u00fcdd\u0259ti ke\u00e7mi\u015f n\u00fcmun\u0259l\u0259rind\u0259n \u0259ld\u0259 edil\u0259n,\u00a0eritrositl\u0259rd\u0259 oksigenin\u00a0da\u015f\u0131nmas\u0131na cavabdeh olan z\u00fclald\u0131r.<\/p>\n
Hemoqlobin x\u00fcsusi qoruyucu kapsulaya yerl\u0259\u015fdirilir ki, bu da s\u00fcni eritrositl\u0259ri stabil saxlay\u0131r v\u0259 viruslardan azad edir. S\u00fcni qan h\u00fcceyr\u0259l\u0259rinin qan qrupuna malik olmamas\u0131 onlar\u0131n uy\u011funluq testi olmadan k\u00f6\u00e7\u00fcr\u00fclm\u0259sin\u0259 imkan verir, bu is\u0259 qan k\u00f6\u00e7\u00fcrm\u0259 prosedurunu xeyli sad\u0259l\u0259\u015fdirir v\u0259 s\u00fcr\u0259tl\u0259ndirir. Daha bir m\u00fch\u00fcm \u00fcst\u00fcnl\u00fck is\u0259 saxlanma m\u00fcdd\u0259tidir. S\u00fcni qan otaq temperaturunda 2 il\u0259 q\u0259d\u0259r, soyuducuda is\u0259 5 il\u0259 q\u0259d\u0259r saxlan\u0131la bil\u0259r. M\u00fcqayis\u0259 \u00fc\u00e7\u00fcn qeyd ed\u0259k ki, donor qan\u0131 soyuducuda c\u0259mi 42 g\u00fcn saxlan\u0131la bilir. \u0130lk klinik s\u0131naqlar h\u0259l\u0259 2022-ci ild\u0259 ba\u015flam\u0131\u015fd\u0131. Ki\u00e7ikmiqyasl\u0131 t\u0259dqiqatlarda 20-50 ya\u015f aras\u0131 sa\u011flam ki\u015fi k\u00f6n\u00fcll\u00fcl\u0259r i\u015ftirak edib.<\/p>\n
Onlara intravenoz \u015f\u0259kild\u0259 artan dozalarla – 100 millilitr\u0259 q\u0259d\u0259r – s\u00fcni oksigen da\u015f\u0131y\u0131c\u0131lar\u0131 (hemoqlobin vezikullar\u0131) yeridilib. B\u0259zi i\u015ftirak\u00e7\u0131larda y\u00fcng\u00fcl yan t\u0259sirl\u0259r m\u00fc\u015fahid\u0259 olunsa da, arterial t\u0259zyiq d\u0259 daxil olmaqla h\u0259yati \u0259h\u0259miyy\u0259tli g\u00f6st\u0259ricil\u0259rd\u0259 ciddi d\u0259yi\u015fiklik qeyd\u0259 al\u0131nmay\u0131b. 2023-c\u00fc ilin mart\u0131nda t\u0259dqiqat geni\u015fl\u0259ndirilib. K\u00f6n\u00fcll\u00fcl\u0259r\u0259 art\u0131q 100-d\u0259n 400 millilitr\u0259 q\u0259d\u0259r s\u00fcni qan h\u00fcceyr\u0259l\u0259ri m\u0259hlulu vurulma\u011fa ba\u015flan\u0131b. Professor Sakai-nin s\u00f6zl\u0259rin\u0259 g\u00f6r\u0259, 2023-c\u00fc ilin iyulunda komanda t\u0259dqiqatlar\u0131n tempini art\u0131r\u0131b. \u018fg\u0259r n\u00f6vb\u0259ti s\u0131naqlar ciddi yan t\u0259sirl\u0259rin olmad\u0131\u011f\u0131n\u0131 t\u0259sdiql\u0259s\u0259, ara\u015fd\u0131rmalar yeni metodun effektivliyi v\u0259 t\u0259hl\u00fck\u0259sizliyinin qiym\u0259tl\u0259ndirilm\u0259sin\u0259 ke\u00e7\u0259c\u0259k. S\u00fcni eritrositl\u0259r t\u0259xmin\u0259n 2030-cu ild\u0259 praktiki tibbd\u0259 t\u0259tbiq oluna bil\u0259r.<\/p>\n